The value of microbiological examination in the diagnosis of pulmonary Aspergillus infection
微生物检验在肺部曲霉菌感染诊断中的价值

摘要

目的 探讨在诊断肺部曲霉菌感染中应用微生物检验的诊断价值。方法 试验者是2018年1月到2022年1月在医院治疗的肺部曲霉菌感染病患数量共50例，以组织病理切片作为检验标准，另采集病患痰液展开培养，取肺泡灌洗液进行G试验，采集静脉血进行GM试验，并将病理检查阳性结果和不同微生物相对比，比较微生物检验对于不同的阳性肺部曲霉菌检查情况。结果 在22例寄生阳性型病患中，GM实验检出率为86.36%，显著高于G试验检出率59.09%及痰液培养检出率27.27%，在28例侵袭阳性型病患中，与痰液培养检出率35.71%相比，G实验及GM实验检出率较高，分别为67.86%、92.86%，P＜0.05。结论以GM实验进行检验，所得检验结果准确率更高，能够为临床诊疗提供可靠依据，利于改善病患预后质量，建议推广。

Abstract

Objective To explore the diagnostic value of microbiological examination in the diagnosis of pulmonary Aspergillus infection.
Methods the subjects were 100 patients with pulmonary Aspergillus infection treated in the hospital from April 2020 to April 2022. The histopathological sections were taken as the test standard. The sputum of patients was collected for culture, the alveolar lavage fluid was taken for G test, and the venous blood was collected for GM test. The positive results of pathological examination were compared with different microorganisms, and the microbiological examination for different positive pulmonary Aspergillus was compared.
Results in 42 patients with parasitic positive type, the detection rate of GM test was 88.10%, which was significantly higher than that of G test 57.14% and sputum culture 35.71%. In 58 patients with invasive positive type, the detection rate of G test and GM test was higher than that of sputum culture 41.38%, the difference was 63.79% and 81.03%, P < 0.05.
Conclusion   the results of GM test are more accurate, which can provide a reliable basis for clinical diagnosis and treatment, and improve the quality of prognosis of patients. It is recommended to popularize it.