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Open Access Article

International Journal of Medicine and Data. 2024; 8: (3) ; 57-60 ; DOI: 10.12208/j.ijmd.20240037.

Research progress of serum HE4 level in endometrial carcinoma
血清HE4水平在子宫内膜癌中的研究进展

作者: 时子菲, 周皓宇, 李颖洁, 翟菲菲, 陈燕 *

华北理工大学临床医学院 河北唐山

*通讯作者: 陈燕,单位:华北理工大学临床医学院 河北唐山;

发布时间: 2024-10-28 总浏览量: 176

摘要

子宫内膜癌(Endometrial Cancer, EC)是女性生殖系统常见的恶性肿瘤之一,其发病率和死亡率在全球范围内均呈上升趋势。近年来,随着血清肿瘤分子标志物研究的深入,血清人附睾蛋白4(HE4)在子宫内膜癌的诊断、病情评估、治疗及预后中的作用日益受到关注。本文就血清HE4水平与子宫内膜癌临床病理特征之间的关系及其临床诊断与预后价值的相关研究进行综述,以期为子宫内膜癌的临床诊断和治疗预后提供理论依据。

关键词: HE4;子宫内膜癌;诊断;临床病理特征;预后

Abstract

Endometrial Cancer (EC) is one of the most common malignancies of the female reproductive system, and its morbidity and mortality are on the rise worldwide. In recent years, with the deepening of the research on serum tumor molecular markers, the role of serum human epididymal protein 4 (HE4) in the diagnosis, evaluation, treatment and prognosis of endometrial cancer has attracted increasing attention. This article reviews the relationship between serum HE4 level and the clinicopathological features of endometrial cancer, as well as its clinical diagnosis and prognostic value, in order to provide theoretical basis for the clinical diagnosis and treatment of endometrial cancer.

Key words: HE4; Endometrial cancer; Diagnosis; Clinicopathological features; prognosis

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引用本文

时子菲, 周皓宇, 李颖洁, 翟菲菲, 陈燕, 血清HE4水平在子宫内膜癌中的研究进展[J]. 国际医学与数据杂志, 2024; 8: (3) : 57-60.