Advances in pharmacological action of Lithospermoside
紫草氰苷的药理作用研究进展

摘要

天葵子别名紫背天葵子、地丁子、天葵根等。天葵子是毛茛科天葵属，多年生草本植物，具有较强的清热解毒、消肿散结及利水通淋等功效，常用于治疗癫痫、咽痛、麻疹不透以及疮疡等病症。紫草氰苷是一种存在于天葵子中的生物碱类化合物，具有抗癌、抗炎、抑菌、降血糖、抗氧化等多种药理作用，在基础及临床研究等医疗领域中拥有广泛的前景 。但作为一种天然药物，紫草氰苷的具体药理分子作用机制尚不明确 ，需要针对各项实验 进行安全性、有效性以及客观性的评价。现将紫草氰苷的药理作用及其分子机制的相关研究进行综述，为探索紫草氰苷的潜在应用价值 及临床应用提供理论依据。

Abstract

Muskroot-like-likeSemiaquilegiaRoot alias purple back sunflower seeds, Diding seeds, sunflower root and so on. Muskroot-like-likeSemiaquilegiaRoot is a perennial herb of the Semiaquilegia in the ranunculaceae family. It has strong effects of clearing heat and detoxification, reducing swelling and dissolving knot, and dissolving water and discoloration. It is often used in the treatment of epilepsy, sore throat, measles and sores and other diseases. Lithospermoside is an alkaloid compound in the Muskroot-like-likeSemiaquilegiaRoot. It has many pharmacological effects such as anticancer, anti-inflammatory, antibacterial, hypoglycemic, antioxidant, etc. It has a wide prospect in basic and clinical research and other medical fields. However, as a natural medicine, the specific pharmacological mechanism of shikoside is still unclear, and it is necessary to evaluate the safety, effectiveness and objectivity of various experiments. In this article, the pharmacological action and molecular mechanism of Lithospermoside are reviewed, which provides theoretical basis for exploring the potential application value and clinical application of Lithospermoside.