摘要
目的 研究分析导致进展性脑梗死的危险因素,并提出针对性干预对策。方法 在2018年1月至2022年1月期间选取研究对象,研究对象的总人数为210例,并且患有急性脑梗死,在患者病情最重时以及入院时填写美国国立卫生院脑卒中量表(NIHSS),根据评分差值将患者分为两组,分别为非进展性脑梗死以及进展性脑梗死,统计患者的临床资料以及各项检查资料,采用Logistic回归分析进展性脑梗死的危险因素。结果 Logistic回归分析显示,发热、白细胞计数、CT早期脑梗死征象、重度脑微出血、糖尿病史、平均动脉压、颈内动脉狭窄、血糖、颅内动脉狭窄、脑分水岭梗死是导致患者发生进展性脑梗死的独立危险因素。结论 发热、白细胞计数、CT早期脑梗死征象、重度脑微出血等10个因素均为进展性脑梗死的独立危险因素,临床医师在为患者实施治疗时需要充分重视,并进行预防。
关键词: 进展性脑梗死;危险因素;干预对策
Abstract
Objective To study and analyze the risk factors of progressive cerebral infarction, and put forward targeted intervention strategies. Methods In January 2018 to January 2022, during the selection of the research object, the object of study of the total number of 210 cases, and patients with acute cerebral infarction, in most patients and hospital to fill in the United States national institutes of health stroke scale (NIHSS) scores, according to the score difference divided the patients into two groups, respectively, the progressive cerebral infarction as well as the progress of cerebral infarction, The clinical data and examination data of the patients were analyzed. Logistic regression was used to analyze the risk factors of progressive cerebral infarction. Results Logistic regression analysis showed that fever, white blood cell count, early CT signs of cerebral infarction, severe cerebral microhemorrhage, history of diabetes, mean arterial pressure, internal carotid artery stenosis, blood glucose, intracranial artery stenosis, and cerebral watershed infarction were independent risk factors for progressive cerebral infarction. Conclusion Fever, white blood cell count, CT signs of early cerebral infarction, severe cerebral microhemorrhage and other 10 factors are independent risk factors for progressive cerebral infarction. Clinicians should pay full attention to the treatment of patients and carry out prevention.
Key words: Progressive cerebral infarction; Risk factors; Intervention countermeasures
参考文献 References
[1] 程坤,刘红,李小梅,等.急性进展性脑梗死患者血浆MMP-9、hs-CRP水平变化及其与颈动脉粥样斑块稳定性的相关性[J].中国实用医刊,2019,46(15):22-24.
[2] 陈娟,万曦,陈玲,等.急性脑梗死患者颈动脉斑块内新生血管超声造影评价及其与血清YKL-40蛋白及Lp-PLA2水平的相关性分析[J].现代生物医学进展,2020,20(15):2877-2881.
[3] 刘运涌,王全保,李伟,等.CD4 CD25免疫调节性T细胞和颈动脉斑块性质与老年进展性脑梗死的相关分析[J].中华老年心脑血管病杂志,2017,19(7):735-737.
[4] 胡月华,郑燕华,唐隽,等.颅内动脉粥样硬化性脑梗死患者外周血CD4^+CD25^+FOXP^(3+)调节性T细胞检测及意义[J].免疫学杂志,2011,27(5):420-423.
[5] 闫振文,郑眉光,李梅.急性脑梗死患者血清补体C1q/肿瘤坏死因子相关蛋白3和白细胞介素6水平与颈总动脉内膜中层厚度的关系[J].中国医药,2020,15(12):1878-1882.
[6] 沈珍贤,曲衎衎,毛智群,等.依达拉奉联合血栓通对急性脑梗死的疗效及对神经功能缺损和日常生活能力的影响[J].现代生物医学进展,2015,0(17):3337-3339.
[7] 潘晓帆,周其达,秦琳.老年急性缺血性脑卒中患者血清中尿酸、总胆红素以及脂蛋白等相关因素的综合性分析[J].中国现代医学杂志,2016,26(18):44-48.
[8] 张锋利,洪芳,张向东.老年高血压脑出血患者早期应用血栓通注射液对超敏C反应蛋白及肿瘤坏死因子-α的影响[J].中国老年学杂志,2016,36(19):4747-4749.
[9] 郗红艳,司志华,李家承,等.ABCD2评分联合颅内近端责任血管狭窄率对短暂性脑缺血发作患者短期进展为脑梗死的风险评估价值研究[J].实用心脑肺血管病杂志,2018,26(12):35-38.
[10] 秋军峰,郭峥.熄风化痰通络汤配合通督调神针刺法对后循环脑梗死患者脑血流、神经损伤标记物、心率变异性和近期预后的影响[J].现代中西医结合杂志,2019,28(14):1514-1518.